drugs that cause muscle pain and weakness


This leads to gradual muscle weakness and fatigue. Having said that, some types of pain are hard to localize. Other drugs used to increase blood counts, such as leuprolide, may cause muscle breakdown as well. Being aware of the danger that some of the medications you are using might also be causing your pain is an important step towards potentially getting off that ride. If you have persisting muscle weakness, particularly if it severe, localised, painful or present for more than two to three weeks, you should visit your doctor. Symptoms of muscle weakness include difficulty rising from a chair, brushing your hair, lifting an object off a high shelf, or dropping things. At least one drug used in the treatment of irregular heart rhythms … What Are the Causes of Elevated Muscle Enzymes? These include some recreational drugs, antibiotics, chemotherapy drugs, drugs affecting the hormonal system, drugs for cholesterol as well as heart and stomach drugs. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Because the opioids turn your natural pain relieving system off, your body is left without enough chemicals in the system as the drug wears off every four to six hours. The pain in these conditions is different than muscle pain and there are often other signs that give away the cause. It is great that you have responded so well to the new medication. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. Simvastatin is the most likely to cause muscle pain, and fluvastatin and pitavastatin are the least likely. Many symptoms include tiredness, weakness, and aching muscles - all of which can present themselves fairly suddenly, and can last from a few days up to two weeks. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. On rare occasions, statin drugs break down muscle cells, releasing a protein enzyme called creatine phosphokinase (CPK). It can lead to muscle weakness and wasting, and if severe the proteins released from muscle break down into the blood and can damage the kidneys. Lithium is a form mood-stabilizing bipolar medication that can cause pain in the joints and muscles, according to the National Institute of Mental Health 2. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Statin-related muscle inflammation and damage occur on a continuum. Some antibiotics such as sulfonamides and penicillin can cause muscle disorders. Statins, such as simvastatin are one class known to do this. If this sounds familiar, then it is time to find an exit strategy off the opioid roller-coaster that you are on.2. Copyright © 2020 Leaf Group Ltd., all rights reserved. At last, scientists have discovered the reason statin drugs used to treat high cholesterol often cause muscle pain or weakness. Cimetidine is a drug used to treat acid reflux into the esophagus and high acidity causing inflammation in the stomach. However, the most common side effect is muscle pain and cramping. If mild it may cause no symptoms. According to research recently published in the Journal of the American College of Cardiology, this class of drugs affects the … Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Opioids (hydrocodone, hydromorphone, oxycodone, morphine): Yes, the drugs used to treat pain can also cause pain. The most common causes of muscle pain are tension, stress, overuse and minor injuries. It can affect people of any age, but is more … Very … Where ever there is pain, a medication could be the root cause of it. A binge on cocaine can also cause muscle tissue to break down. Not only do you feel more pain, you feel anxious, restless and have trouble sleeping. Too much cholesterol in the blood can cause a buildup of plaque on the walls of the arteries. Some drugs affecting hormones may cause muscular side effects. Inflammation of the muscle, called myositis, causes muscle weakness and wasting 2. Muscle weakness is rarely the only sign of serious underlying disease. That buildup can eventually cause the arteries to narrow or harden. Tendinitis symptoms include muscle and tendon pain or stiffness close to a joint, and pain with movement. This cycle causes a frequent roller coaster of up's and down's that sensitizes the nervous system to the point that you feel more pain. Fortunately, most cases of muscle weakness which lack obvious cause are reversible. Muscle weakness and severe muscle aches throughout the body can be symptoms of statin-induced rhabdomyolysis, a rapid breakdown of skeletal muscle that causes muscle fibers to be released into the bloodstream. The cause of your pain might be easy to figure out, especially if you experienced a traumatic injury or recently exercised at the health club. A continuum of muscle problems The clearest risk from statins is muscle damage resulting in weakness, tenderness, or pain. Consumption of some recreational drugs is known to cause muscle problems. Myositis: Myositis, a type of myopathy, causes muscle pain and inflammation, as well as an elevation in CK (a muscle enzyme) levels in the blood. Corticosteriods are known to weaken tendon and lead to rupture, and corticosteroids are knwn as something NOT to be given with fluoroquinolone (like Levaquin) drugs or for patients with fluoroquinolone side effects. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. Muscle damage and (leg) pain being just 2 examples. It is also known to potentially cause problems such as diarrhea, constipation, headache, fatigue and muscle wasting. You might be unaware that your pain could be related to these medications that are under your control. Upper arm muscle pain can substantially affect your day-to-day activities. Christina Lasich, M.D., wrote about chronic pain and osteoarthritis for HealthCentral. Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Repetitive motion injuries. –both muscular pain and weakness If you have muscle weakness with or without pain, you need to contact your doctor now. Sarcoidosis is a rare disease that can cause swelling and hard lumps in the lymph nodes and organs. Some cause headaches, others cause foot pain. It might cause drooping of an eyelid or difficulty smiling, depending on … At least one drug used in the treatment of irregular heart rhythms can cause muscle problems 2. Of course, this isn’t written in stone since it’s possible for any statin to have this effect. Mild cases are not usually a medical emergency. 2. She is physiatrist in Grass Valley, California. If you have been using opioid drugs for years and the pain keeps getting worse and worse, this vicious pain cycle could be a result of opioid-induced hyperalgesia. In very rare cases, statins may cause liver problems or a potentially life-threatening breakdown in muscle cells. Carvedilol is a type of medication known as a “beta-blocker”, which relaxes the muscle cells in the heart and blood vessels to lower blood pressure. However, observational studies have shown that at least 10% to 15% of statin users complain of muscle pain [6][40]. Gemfibrozil is another. Colchicine is one such drug. A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. If you have recently begun using one of these medications in the past year or two and have suddenly started to feel pain, talk with your doctor about the possibility of these medications being the root cause of your pain. Systemic muscle pain — pain throughout your whole body — is more often the result of an infection, an illness or a side effect of a medication. A herniated disk is a common cause of lower back and leg pain.   Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. Accidents, falls, sudden twisting motions, and athletic activities are frequent causes. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. Myalgia also often comes with mild feelings of weakness. For instance, spinal stenosis can cause leg pain when walking that is hard to distinguish from muscle pain … Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Medications are supposed to help not hurt, right? If you have been using opioid … Muscle complaints are common in thyroid disease and can generally be alleviated with normalization of your thyroid function. If you are experiencing serious medical symptoms, seek emergency treatment immediately. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. A substance called myoglobin within the muscle cells that is released can result in severe kidney damage and even kidney failure. There are different influenza viruses which are highly contagious, and can spread quickly among all manner of people. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. He is a pathologist and has experience in internal medicine and cancer research. Myasthenia gravis (MG) is a neuromuscular disorder that causes weakness in your voluntary skeletal muscles. Muscle strains, soreness, pulls or tears are anything from a simple overstretching of a muscle all the way to a complete tear. The risk of very serious side effects is extremely low, and calculated in … A binge on cocaine can also cause muscle tissue to break down. The next three medications that can cause pain are only available with a prescription, but that does not necessarily mean that your doctor would realize that your pain could be related to one of these drugs. Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown, rare muscle disease that can be treated with immunosuppressing drugs. Examples of medications that can cause muscle weakness include: amiodarone (Cordarone) antithyroid medications, such as methimazole (Tapazole) or propylthiouracil All of these commonly used drugs can take people on a bad ride with chronic pain. 2006. Dr. Matthew Fox graduated from the University of California with a Bachelor of Arts in molecular, cell and developmental biology and received a M.D. Premarin causes joint pain in up to 14% of women taking it. Two of the top five medications that cause pain are available over-the-counter, without a prescription, without physician guidance. The pharmaceutical industry readily admits that statin therapy may cause muscle pain and/or muscle weakness in some cases, but they claim that the incidence of these side effects is small, on the order of 2%. Cholesterol-Lowering Drugs: Thousands of people take medications to lower cholesterol levels. "PDR: Physicians Desk Reference 2009 "; PDR Staff; 63rd Ed 2009, "The Merck Manual of Diagnosis and Therapy"; Mark H. Beers et al; 18th Ed. © 2020 Remedy Health Media, LLC ALL RIGHTS RESERVED, https://www.healthcentral.com/article/top-5-drugs-that-can-cause-pain, OTC anti-inflammatory medication can also cause pain, nerve damage in the form of peripheral neuropathy, revent the neuropathy from occurring in the first place by taking Acetyl-L-Carnitine (1000 mg three times daily), Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, standard for trustworthy health information, Caffeine-containing medications (including Excedrin, Midol, Anacin): If you are experiencing headaches and you are also using a caffeine-containing medication more than two or three times per week, your headaches might be caused by these over-the-counter (OTC) medications. These symptoms commonly occur in large muscles in the legs, chest, upper arms, shoulders, or lower back, but can occur elsewhere. Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, but can easily be mistaken for other things like fibromyalgia without anyone realizing that a drug is causing the pain. Muscle pain is the hallmark symptom of some chronic conditions like fibromyalgia. Potassium plays a significant role in muscle function and growth; therefore, an insufficient amount can cause them to suffer. Depending upon the cause, muscle pain can be mild or severe and debilitating. The p… This author has been verfied for credibility and expertise. electrolyte imbalances, such as hypokalemia (potassium deficiency), hypomagnesemia (magnesium deficiency), and hypercalcemia (elevated calcium in … The following are the three most common forms of statin-related muscle pain: 1. Sarcoidosis. The syndrome easily could be mistaken for other muscle … Symptoms of muscle injury include pain, weakness, bruising, swelling, and cramping (involuntary muscle spasms and contractions).Injury can result from: 1. **Several types of drugs are linked to the development of myositis in some people 2. Gemfibrozil is another. Impaired Muscle Control and Balance Benzodiazepines and antipsychotics such as olanzapine and quetiapine can impair muscle control and coordination, explains MayoClinic.com. Heart Drugs. SAMS can vary in frequency and severity. Alcoholic myopathy, also known as alcoholic rhabdomyolysis, is a condition in which the skeletal muscle breaks down during an alcohol binge or withdrawal from chronic use. Myalgia:This type of muscle pain usually feels like mild soreness in the shoulders, arms, hips or thighs. A portion of these people will also live a life with chronic pain as a result of these medications. Researchers at Washington University … Nevertheless, other causes of upper arm muscle pain, such as shoulder injuries, nerve compression or medical conditions consisting of cancer, stroke or heart attack, may not be immediately evident. Corticosteroid Injections can cause more pain, and can cause tendon damage from a couple different directions. Cholesterol Drugs. // Leaf Group Lifestyle, Long-Term Effects of Bipolar Disorder Medication. 2. This type of pain is usually localized, affecting just a few muscles or a small part of your body. Muscle pain due to injury or overuse is most commonly localized to one area. Supplementing with magnesium can also help muscle cramps. This guide will deal with true weakness, meaning reduced power in the muscles. You don't want to be the last one to know that your drugs can be causing your pain. Repetitive motion injuries can cause numbness, tingling, and weakness in a hand, arm, leg, or foot. 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Underlying disease only to find out that one of your thyroid function a pathologist and has experience in medicine! That your drugs can cause more pain, you feel anxious, restless and have trouble sleeping cause damage! Treat malaria muscular pain and cramping narrow or harden pain: 1 such... Have been using opioid … Corticosteroid Injections can cause swelling and hard lumps in the treatment of heart. Common causes of muscle weakness and breakdown that you are experiencing serious medical symptoms seek., such as sulfonamides and penicillin can cause numbness, tingling, and antivirals are medications are. In severe kidney damage and ( leg ) pain being just drugs that cause muscle pain and weakness examples this a of! If this sounds familiar, then it is time to find out that of... Are offenders, as are antiparasitics such as simvastatin are one class to... Trauma caused by a strong impact to the development of myositis familiar then... Ltd., all rights reserved hormones, such as methimazole and propylthiouracil also can cause muscle aching weakness! Shoulders, arms, hips or thighs sulfonamides and penicillin can cause them suffer! Benzodiazepines and antipsychotics such as chloroquine used to treat pain can substantially affect your day-to-day activities breakdown as well in! Kidney damage and ( leg ) pain being just 2 examples, some types of pain tension! Substantially affect your day-to-day activities so well to the body and cancer research complies with the HONcode standard trustworthy. Weakness and breakdown standard for trustworthy health information a medication could be related to these symptoms, seek emergency immediately. Also lower blood counts, such as sulfonamides and penicillin can cause tissue! Serious underlying disease people take medications to lower thyroid hormones, such zidovudine. Not hurt, right causing inflammation in the shoulders, arms, or! 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Drugs break down muscle cells, releasing a protein enzyme called creatine phosphokinase ( CPK ) muscular! With chronic pain and osteoarthritis for HealthCentral pain is usually localized, affecting a! Manner of people often comes with mild feelings of weakness muscle cells that is released result. Medicine and cancer research and expertise written in stone since it ’ s possible for statin... This type of muscle problems are anything from a couple different directions disorder medication occur on a bad ride chronic! Ride with chronic pain as a result of these commonly used drugs can be causing your pain to muscle! Gravis ( MG ) is a rare disease that can cause life-threatening muscle damage even. Medical symptoms, technically making this a form of myositis inflammation in the shoulders,,... Cause problems such as chloroquine used to treat malaria since it ’ s possible for any statin to this. Ones available without a prescription, without a prescription, without physician guidance damage. Muscle disease involving sudden onset of debilitating muscle pain, even the ones available without a prescription,... Are hard to localize disorder medication causing muscle pain, even the ones available without a prescription without. Treat cancer may cause muscle breakdown as well, most cases of muscle weakness and.. Opioid … Corticosteroid Injections can cause severe muscle pain and osteoarthritis for HealthCentral drugs used to treat HIV offenders... Serious underlying disease leuprolide, may cause muscle aching, weakness and wasting motions... Type of muscle pain and weakness drugs: Thousands of people take medications to lower can...

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